Cardiac Medicine Certification (CMC) Practice Exam

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Which medication is classified as an Angiotensin II Receptor Blocker (ARB)?

  1. Enalapril

  2. Lisinopril

  3. Losartan

  4. Captopril

The correct answer is: Losartan

Losartan is classified as an Angiotensin II Receptor Blocker (ARB) because it selectively inhibits the action of angiotensin II, a hormone that plays a pivotal role in regulating blood pressure and fluid balance in the body. By blocking the receptors that angiotensin II binds to, Losartan helps to relax blood vessels, lower blood pressure, and reduce the workload on the heart. In contrast, the other medications listed are all classified as ACE inhibitors, which function by inhibiting the angiotensin-converting enzyme (ACE). This enacts a different mechanism of action that ultimately reduces levels of angiotensin II, but does not specifically block its receptors as Losartan does. This distinction is crucial for understanding the pharmacological differences in managing conditions such as hypertension and heart failure.