What should be monitored in patients receiving digoxin therapy?

Monitoring serum digoxin levels and renal function in patients receiving digoxin therapy is crucial for several reasons. Digoxin has a narrow therapeutic index, which means that the difference between an effective dose and a toxic dose is very small. Regular monitoring of serum digoxin levels helps ensure that patients remain within the therapeutic range, as both subtherapeutic levels and toxicity can lead to serious complications.

Additionally, renal function is particularly important because digoxin is primarily eliminated by the kidneys. Impaired renal function can lead to accumulation of digoxin in the body, increasing the risk of toxicity. Thus, monitoring renal function helps in adjusting the dosage appropriately and ensures patient safety during digoxin therapy.

In contrast, while monitoring platelet count and liver enzymes, electrolyte levels and blood glucose, or heart rate and blood pressure can provide valuable information about a patient's overall health or other specific conditions, they do not directly address the critical aspects of digoxin therapy. Monitoring the serum digoxin levels and renal function is essential for optimizing therapy and preventing adverse effects specifically related to digoxin.